Circulating Interleukin-8 levels explain breast cancer osteolysis in mice and humans

Skeletal metastases of breast cancer and subsequent osteolysis connote a dramatic change in the prognosis for the patient and significantly increase the morbidity associated with disease. The cytokine Interleukin 8 (IL-8/CXCL8) is able to directly stimulate osteoclastogenesis and bone resorption in...

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Detalhes bibliográficos
Main Authors: Kamalakar, Archana, Bendre, Manali S., Washam, Charity L., Fowler, Tristan W., Carver, Adam, Dilley, Joshua D., Bracey, John W., Akel, Nisreen S., Margulies, Aaron G., Skinner, Robert A., Swain, Frances L., Hogue, William R., Montgomery, Corey O., Lahiji, Parshawn, Maher, Jacqueline J., Leitzel, Kim E., Ali, Suhail M., Lipton, Alan, Nicholas, Richard W., Gaddy, Dana, Suva, Larry J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3967592/
https://ncbi.nlm.nih.gov/pubmed/24486955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2014.01.015
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