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Pediatric Dosing and Body Size in Biotherapeutics

Although pediatric doses for biotherapeutics are often based on patients' body weight (mg/kg) or body surface area (mg/m(2)), linear body size dose adjustment is highly empirical. Growth and maturity are also important factors that affect the absorption, distribution, metabolism and excretion (...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Shi, Rong, Derendorf, Hartmut
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3967145/
https://ncbi.nlm.nih.gov/pubmed/27721364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics2040389
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