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Pediatric Dosing and Body Size in Biotherapeutics
Although pediatric doses for biotherapeutics are often based on patients' body weight (mg/kg) or body surface area (mg/m(2)), linear body size dose adjustment is highly empirical. Growth and maturity are also important factors that affect the absorption, distribution, metabolism and excretion (...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
MDPI
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3967145/ https://ncbi.nlm.nih.gov/pubmed/27721364 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics2040389 |
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