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New insights into the regulation of Axin function in canonical Wnt signaling pathway

The Wnt signaling pathway plays crucial roles during embryonic development, whose aberration is implicated in a variety of human cancers. Axin, a key component of canonical Wnt pathway, plays dual roles in modulating Wnt signaling: on one hand, Axin scaffolds the “β-catenin destruction complex” to p...

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Bibliographic Details
Main Authors: Song, Xiaomin, Wang, Sheng, Li, Lin
Format: Artigo
Language:Inglês
Published: Higher Education Press 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3967064/
https://ncbi.nlm.nih.gov/pubmed/24474204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-014-0019-2
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