CS1-Specific Chimeric Antigen Receptor (CAR)-Engineered Natural Killer Cells Enhance In Vitro and In Vivo Anti-tumor Activity Against Human Multiple Myeloma

Multiple myeloma (MM) is an incurable hematological malignancy. Chimeric antigen receptor (CAR)-expressing T cells have been demonstrated successful in the clinic to treat B-lymphoid malignancies. However, the potential utility of antigen-specific CAR-engineered natural killer (NK) cells to treat MM...

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Detalhes bibliográficos
Main Authors: Chu, Jianhong, Deng, Youcai, Benson, Don M., He, Shun, Hughes, Tiffany, Zhang, Jianying, Peng, Yong, Mao, Hsiaoyin, Yi, Ling, Ghoshal, Kalpana, He, Xiaoming, Devine, Steven M., Zhang, Xiaoliu, Caligiuri, Michael A., Hofmeister, Craig C., Yu, Jianhua
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3967004/
https://ncbi.nlm.nih.gov/pubmed/24067492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2013.279
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