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Nrf2 activation-induced hepatic VLDLR overexpression in response to oxidative stress contributes to alcoholic liver disease in mice

Chronic alcohol consumption leads to hypertriglyceridemia, which is positively associated with alcoholic liver disease (ALD). However, whether and how it contributes to the development of fatty liver and liver injury are largely unknown. In this study, we demonstrate that chronic alcohol exposure di...

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Main Authors: Wang, Zhigang, Dou, Xiaobing, Li, Songtao, Zhang, Ximei, Sun, Xinguo, Zhou, Zhanxiang, Song, Zhenyuan
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3966965/
https://ncbi.nlm.nih.gov/pubmed/24170703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.26912
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