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Protection of Nicotinic Acid against Oxidative Stress-Induced Cell Death in Hepatocytes Contributes to Its Beneficial Effect on Alcohol-induced Liver Injury in Mice

Oxidative stress plays a pathological role in the development of alcoholic liver disease. In this study, we investigated the effects of nicotinic acid (NA) supplementation on H(2)O(2)-induced cell death in hepatocytes and alcohol-induced liver injury in mice. Hepatocytes were exposed to H(2)O(2) (0–...

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Detalhes bibliográficos
Main Authors: Dou, Xiaobing, Shen, Chen, Wang, Zhigang, Li, Songtao, Zhang, Ximei, Song, Zhenyuan
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3679291/
https://ncbi.nlm.nih.gov/pubmed/23465591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jnutbio.2012.12.012
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