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Lipoxin A4 and Platelet Activating Factor Are Involved in E. coli or LPS-Induced Lung Inflammation in CFTR-Deficient Mice

CFTR (cystic fibrosis transmembrane conductance regulator) is expressed by both neutrophils and platelets. Lack of functional CFTR could lead to severe lung infection and inflammation. Here, we found that mutation of CFTR (F508del) or inhibition of CFTR in mice led to more severe thrombocytopenia, a...

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Main Authors: Wu, Haiya, Yang, Jun, Su, Emily M., Li, Ling, Zhao, Caiqi, Yang, Xi, Gao, Zhaowei, Pan, Mengyao, Sun, Peiyu, Sun, Wei, Jiang, Yiyi, Su, Xiao
格式: Artigo
語言:Inglês
出版: Public Library of Science 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3966846/
https://ncbi.nlm.nih.gov/pubmed/24671173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093003
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