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Lipoxin A4 and Platelet Activating Factor Are Involved in E. coli or LPS-Induced Lung Inflammation in CFTR-Deficient Mice

CFTR (cystic fibrosis transmembrane conductance regulator) is expressed by both neutrophils and platelets. Lack of functional CFTR could lead to severe lung infection and inflammation. Here, we found that mutation of CFTR (F508del) or inhibition of CFTR in mice led to more severe thrombocytopenia, a...

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מידע ביבליוגרפי
Main Authors: Wu, Haiya, Yang, Jun, Su, Emily M., Li, Ling, Zhao, Caiqi, Yang, Xi, Gao, Zhaowei, Pan, Mengyao, Sun, Peiyu, Sun, Wei, Jiang, Yiyi, Su, Xiao
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2014
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3966846/
https://ncbi.nlm.nih.gov/pubmed/24671173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093003
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