Effects of Huanglian-Jie-Du-Tang and Its Modified Formula on the Modulation of Amyloid-β Precursor Protein Processing in Alzheimer's Disease Models

Huanglian-Jie-Du-Tang (HLJDT) is a famous traditional Chinese herbal formula that has been widely used clinically to treat cerebral ischemia. Recently, we found that berberine, a major alkaloid compound in HLJDT, reduced amyloid-β (Aβ) accumulation in an Alzheimer’s disease (AD) mouse model. In this...

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Detalhes bibliográficos
Main Authors: Durairajan, Siva Sundara Kumar, Huang, Ying-Yu, Yuen, Pui-Yee, Chen, Lei-Lei, Kwok, Ka-Yan, Liu, Liang-Feng, Song, Ju-Xian, Han, Quan-Bin, Xue, Lei, K. Chung, Sookja, Huang, Jian-Dong, Baum, Larry, Senapati, Sanjib, Li, Min
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3966845/
https://ncbi.nlm.nih.gov/pubmed/24671102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0092954
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