Impact of myeloperoxidase-LDL interactions on enzyme activity and subsequent posttranslational oxidative modifications of apoB-100

Oxidation of LDL by the myeloperoxidase (MPO)-H(2)O(2)-chloride system is a key event in the development of atherosclerosis. The present study aimed at investigating the interaction of MPO with native and modified LDL and at revealing posttranslational modifications on apoB-100 (the unique apolipopr...

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Main Authors: Delporte, Cédric, Boudjeltia, Karim Zouaoui, Noyon, Caroline, Furtmüller, Paul G., Nuyens, Vincent, Slomianny, Marie-Christine, Madhoun, Philippe, Desmet, Jean-Marc, Raynal, Pierre, Dufour, Damien, Koyani, Chintan N., Reyé, Florence, Rousseau, Alexandre, Vanhaeverbeek, Michel, Ducobu, Jean, Michalski, Jean-Claude, Nève, Jean, Vanhamme, Luc, Obinger, Christian, Malle, Ernst, Van Antwerpen, Pierre
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Biochemistry and Molecular Biology 2014
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3966708/
https://ncbi.nlm.nih.gov/pubmed/24534704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M047449
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