Myeloperoxidase-catalyzed oxidation of cyanide to cyanate: A potential carbamylation route involved in the formation of atherosclerotic plaques?

Protein carbamylation by cyanate is a post-translational modification associated with several (patho)physiological conditions, including cardiovascular disorders. However, the biochemical pathways leading to protein carbamylation are incompletely characterized. This work demonstrates that the heme p...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Delporte, Cédric, Zouaoui Boudjeltia, Karim, Furtmüller, Paul G., Maki, Richard A., Dieu, Marc, Noyon, Caroline, Soudi, Monika, Dufour, Damien, Coremans, Catherine, Nuyens, Vincent, Reye, Florence, Rousseau, Alexandre, Raes, Martine, Moguilevsky, Nicole, Vanhaeverbeek, Michel, Ducobu, Jean, Nève, Jean, Robaye, Bernard, Vanhamme, Luc, Reynolds, Wanda F., Obinger, Christian, Van Antwerpen, Pierre
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Enzymology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5925816/
https://ncbi.nlm.nih.gov/pubmed/29496995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.801076
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