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The Past, Present, and Future of Human Centromere Genomics

The centromere is the chromosomal locus essential for chromosome inheritance and genome stability. Human centromeres are located at repetitive alpha satellite DNA arrays that compose approximately 5% of the genome. Contiguous alpha satellite DNA sequence is absent from the assembled reference genome...

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Bibliographic Details
Main Authors: Aldrup-MacDonald, Megan E., Sullivan, Beth A.
Format: Artigo
Language:Inglês
Published: MDPI 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3966626/
https://ncbi.nlm.nih.gov/pubmed/24683489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes5010033
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