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The Past, Present, and Future of Human Centromere Genomics

The centromere is the chromosomal locus essential for chromosome inheritance and genome stability. Human centromeres are located at repetitive alpha satellite DNA arrays that compose approximately 5% of the genome. Contiguous alpha satellite DNA sequence is absent from the assembled reference genome...

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Autori principali: Aldrup-MacDonald, Megan E., Sullivan, Beth A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3966626/
https://ncbi.nlm.nih.gov/pubmed/24683489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes5010033
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