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The Past, Present, and Future of Human Centromere Genomics

The centromere is the chromosomal locus essential for chromosome inheritance and genome stability. Human centromeres are located at repetitive alpha satellite DNA arrays that compose approximately 5% of the genome. Contiguous alpha satellite DNA sequence is absent from the assembled reference genome...

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Detalhes bibliográficos
Main Authors: Aldrup-MacDonald, Megan E., Sullivan, Beth A.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3966626/
https://ncbi.nlm.nih.gov/pubmed/24683489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes5010033
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