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The Past, Present, and Future of Human Centromere Genomics

The centromere is the chromosomal locus essential for chromosome inheritance and genome stability. Human centromeres are located at repetitive alpha satellite DNA arrays that compose approximately 5% of the genome. Contiguous alpha satellite DNA sequence is absent from the assembled reference genome...

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Détails bibliographiques
Auteurs principaux: Aldrup-MacDonald, Megan E., Sullivan, Beth A.
Format: Artigo
Langue:Inglês
Publié: MDPI 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3966626/
https://ncbi.nlm.nih.gov/pubmed/24683489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes5010033
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