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A Localized Wnt Signal Orients Asymmetric Stem Cell Division in Vitro
Developmental signals such as Wnts are often presented to cells in an oriented manner. To examine the consequences of local Wnt signaling, we immobilized Wnt proteins on beads and introduced them to embryonic stem cells in culture. At the single-cell level, the Wnt-bead induced asymmetric distributi...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3966430/ https://ncbi.nlm.nih.gov/pubmed/23520113 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1231077 |
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