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A Localized Wnt Signal Orients Asymmetric Stem Cell Division in Vitro

Developmental signals such as Wnts are often presented to cells in an oriented manner. To examine the consequences of local Wnt signaling, we immobilized Wnt proteins on beads and introduced them to embryonic stem cells in culture. At the single-cell level, the Wnt-bead induced asymmetric distributi...

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Bibliografske podrobnosti
Main Authors: Habib, Shukry J., Chen, Bi-Chang, Tsai, Feng-Chiao, Anastassiadis, Konstantinos, Meyer, Tobias, Betzig, Eric, Nusse, Roel
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3966430/
https://ncbi.nlm.nih.gov/pubmed/23520113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1231077
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