Diet‐induced obesity in mice reduces placental efficiency and inhibits placental mTOR signaling

As in humans, obesity during pregnancy in mice results in elevated maternal insulin levels and metabolic programming of offspring. mTOR signaling regulates amino acid transport and may function as a placental nutrient sensor. Because obesity is a condition with increased nutrient availability, we hy...

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Hlavní autoři: Lager, Susanne, Samulesson, Anne‐Maj, Taylor, Paul D., Poston, Lucilla, Powell, Theresa L., Jansson, Thomas
Médium: Artigo
Jazyk:Inglês
Vydáno: Wiley Periodicals, Inc. 2014
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3966251/
https://ncbi.nlm.nih.gov/pubmed/24744907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/phy2.242
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