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Quantification of mitochondrial toxicity in HIV-infected individuals by quantitative PCR compared to flow cytometry

BACKGROUND: Non-invasive diagnostic assays to evaluate mitochondrial toxicity could have significant clinical utility for HIV-infected individuals on antiretroviral therapy (ART). METHODS: This study compared the ratio of mitochondrial to nuclear DNA determined by quantitative PCR to the ratio of mi...

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Detalles Bibliográficos
Main Authors: Wagner, Thor A., Lin, Chen-Han, Tobin, Nicole H., Côté, Hélène C.F., Sloan, Derek D., Jerome, Keith R., Frenkel, Lisa M.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3966180/
https://ncbi.nlm.nih.gov/pubmed/23044657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cyto.b.21045
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