Cyclodextrin and Polyethylenimine Functionalized Mesoporous Silica Nanoparticles for Delivery of siRNA Cancer Therapeutics

Effective delivery holds the key to successful in vivo application of therapeutic small interfering RNA (siRNA). In this work, we have developed a universal siRNA carrier consisting of a mesoporous silica nanoparticle (MSNP) functionalized with cyclodextrin-grafted polyethylenimine (CP). CP provides...

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Autori principali: Shen, Jianliang, Kim, Han-Cheon, Su, Hua, Wang, Feng, Wolfram, Joy, Kirui, Dickson, Mai, Junhua, Mu, Chaofeng, Ji, Liang-Nian, Mao, Zong-Wan, Shen, Haifa
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ivyspring International Publisher 2014
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3966054/
https://ncbi.nlm.nih.gov/pubmed/24672582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.8263
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