Cyclodextrin and Polyethylenimine Functionalized Mesoporous Silica Nanoparticles for Delivery of siRNA Cancer Therapeutics

Effective delivery holds the key to successful in vivo application of therapeutic small interfering RNA (siRNA). In this work, we have developed a universal siRNA carrier consisting of a mesoporous silica nanoparticle (MSNP) functionalized with cyclodextrin-grafted polyethylenimine (CP). CP provides...

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Hlavní autoři: Shen, Jianliang, Kim, Han-Cheon, Su, Hua, Wang, Feng, Wolfram, Joy, Kirui, Dickson, Mai, Junhua, Mu, Chaofeng, Ji, Liang-Nian, Mao, Zong-Wan, Shen, Haifa
Médium: Artigo
Jazyk:Inglês
Vydáno: Ivyspring International Publisher 2014
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Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3966054/
https://ncbi.nlm.nih.gov/pubmed/24672582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.8263
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