載入...
EZH2-mediated H3K27 trimethylation mediates neurodegeneration in ataxia-telangiectasia
The symptoms of ataxia-telangiectasia (A-T) include a progressive neurodegeneration caused by ATM protein deficiency. We previously found that nuclear accumulation of histone deacetylase-4, HDAC4, contributes to this degeneration; we now report that increased histone H3K27 trimethylation (H3K27me3)...
Na minha lista:
| Main Authors: | , , , , , |
|---|---|
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2013
|
| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3965909/ https://ncbi.nlm.nih.gov/pubmed/24162653 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3564 |
| 標簽: |
添加標簽
沒有標簽, 成為第一個標記此記錄!
|