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Stimulation of intrachromosomal homologous recombination in human cells by electroporation with site-specific endonucleases.

In somatic mammalian cells, homologous recombination is a rare event. To study the effects of chromosomal breaks on frequency of homologous recombination, site-specific endonucleases were introduced into human cells by electroporation. Cell lines with a partial duplication within the HPRT (hypoxanth...

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Publikašuvnnas:Proc Natl Acad Sci U S A
Váldodahkkit: Brenneman, M, Gimble, F S, Wilson, J H
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: National Academy of Sciences 1996
Fáttát:
Liŋkkat:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39658/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8622983/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.8.3608
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