Stimulation of intrachromosomal homologous recombination in human cells by electroporation with site-specific endonucleases.
In somatic mammalian cells, homologous recombination is a rare event. To study the effects of chromosomal breaks on frequency of homologous recombination, site-specific endonucleases were introduced into human cells by electroporation. Cell lines with a partial duplication within the HPRT (hypoxanth...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1996
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39658/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8622983/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.8.3608 |
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