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Dose optimisation of antibiotics in children: application of pharmacokinetics/pharmacodynamics in paediatrics

The judicious use of antibiotics to combat infections in children relies upon appropriate selection of an agent, dose and duration to maximise efficacy and to minimise toxicity. Critical to dose optimisation is an understanding of the pharmacokinetics and pharmacodynamics of available drugs. Optimal...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Downes, Kevin J., Hahn, Andrea, Wiles, Jason, Courter, Joshua D., Vinks, Alexander A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3965635/
https://ncbi.nlm.nih.gov/pubmed/24389079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijantimicag.2013.11.006
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