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Granulocytes Affect Double-Strand Break Repair Assays in Primary Human Lymphocytes

Patients who develop therapy-related myelodysplasia/acute myeloid leukemia after autologous-hematopoietic stem cell (aHCT) transplant show lower expression levels of DNA repair genes in their pre-aHCT CD34(+) cells. To investigate whether this leads to functional differences in DNA repair abilities...

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Detalhes bibliográficos
Main Authors: Lacoste, Sandrine, Bhatia, Ravi, Bhatia, Smita, O'Connor, Timothy R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3965556/
https://ncbi.nlm.nih.gov/pubmed/24667872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093185
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