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Inhibition of Cathepsin B by E-64 Induces Oxidative Stress and Apoptosis in Filarial Parasite
BACKGROUND: Current available antifilarial drug strategies only eliminate the larval stages of filarial parasites. Therefore, there is an urgent need of drugs which are macrofilaricidals. Identification of molecular targets crucial for survival of parasite is a prerequisite for drug designing. Cathe...
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Main Authors: | , , |
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格式: | Artigo |
語言: | Inglês |
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Public Library of Science
2014
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在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3965533/ https://ncbi.nlm.nih.gov/pubmed/24667798 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093161 |
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