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Inhibition of Cathepsin B by E-64 Induces Oxidative Stress and Apoptosis in Filarial Parasite

BACKGROUND: Current available antifilarial drug strategies only eliminate the larval stages of filarial parasites. Therefore, there is an urgent need of drugs which are macrofilaricidals. Identification of molecular targets crucial for survival of parasite is a prerequisite for drug designing. Cathe...

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書目詳細資料
Main Authors: Wadhawan, Mohit, Singh, Neetu, Rathaur, Sushma
格式: Artigo
語言:Inglês
出版: Public Library of Science 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3965533/
https://ncbi.nlm.nih.gov/pubmed/24667798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093161
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