Polymorphisms at Residue 222 of the Hemagglutinin of Pandemic Influenza A(H1N1)pdm09: Association of Quasi-Species to Morbidity and Mortality in Different Risk Categories

The D222G substitution in the hemagglutinin (HA) gene of the pandemic influenza A(H1N1)pdm09 virus has been identified as a potential virulence marker, because this change allows for virus invasion deeper into the respiratory tract. In this study, we analyzed D, G and N polymorphisms at residue 222...

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Hauptverfasser: Resende, Paola Cristina, Motta, Fernando C., Oliveira, Maria de Lourdes A., Gregianini, Tatiana S., Fernandes, Sandra B., Cury, Ana Luisa F., do Carmo D. Rosa, Maria, Souza, Thiago Moreno L., Siqueira, Marilda M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3965456/
https://ncbi.nlm.nih.gov/pubmed/24667815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0092789
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