A(H1N1)pdm09 hemagglutinin D222G and D222N variants are frequently harbored by patients requiring extracorporeal membrane oxygenation and advanced respiratory assistance for severe A(H1N1)pdm09 infection

BACKGROUND: In patients with A(H1N1)pdm09 infection, severe lung involvement requiring admission to intensive care units (ICU) has been reported. Mutations at the hemagglutinin (HA) receptor binding site (RBS) have been associated with increased virulence and disease severity, representing a potenti...

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Detalhes bibliográficos
Publicado no:Influenza Other Respir Viruses
Main Authors: Ruggiero, Tina, De Rosa, Francesco, Cerutti, Francesco, Pagani, Nicole, Allice, Tiziano, Stella, Maria L., Milia, Maria G., Calcagno, Andrea, Burdino, Elisa, Gregori, Gabriella, Urbino, Rosario, Di Perri, Giovanni, Ranieri, Marco V., Ghisetti, Valeria
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2013
Assuntos:
Part 5
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4634302/
https://ncbi.nlm.nih.gov/pubmed/23927713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/irv.12146
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