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Association of Variants at BCL11A and HBS1L-MYB with Hemoglobin F and Hospitalization Rates among Sickle Cell Patients in Cameroon

BACKGROUND: Genetic variation at loci influencing adult levels of HbF have been shown to modify the clinical course of sickle cell disease (SCD). Data on this important aspect of SCD have not yet been reported from West Africa. We investigated the relationship between HbF levels and the relevant gen...

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Библиографические подробности
Главные авторы: Wonkam, Ambroise, Ngo Bitoungui, Valentina J., Vorster, Anna A., Ramesar, Raj, Cooper, Richard S., Tayo, Bamidele, Lettre, Guillaume, Ngogang, Jeanne
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3965431/
https://ncbi.nlm.nih.gov/pubmed/24667352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0092506
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