Association between Variants at BCL11A Erythroid-Specific Enhancer and Fetal Hemoglobin Levels among Sickle Cell Disease Patients in Cameroon: Implications for Future Therapeutic Interventions

Variants in BCL11A were previously associated with fetal hemoglobin (HbF) levels among Cameroonian sickle cell disease (SCD) patients, however explaining only ∼2% of the variance. In the same patients, we have investigated the relationship between HbF and two SNPs in a BCL11A erythroid-specific enha...

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Detalhes bibliográficos
Publicado no:OMICS
Main Authors: Pule, Gift Dineo, Ngo Bitoungui, Valentina Josiane, Chemegni, Bernard Chetcha, Kengne, Andre Pascal, Antonarakis, Stylianos, Wonkam, Ambroise
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2015
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615773/
https://ncbi.nlm.nih.gov/pubmed/26393293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/omi.2015.0124
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