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Positive Feedback Regulation of Proliferation in Vascular Smooth Muscle Cells Stimulated by Lipopolysaccharide Is Mediated through the TLR 4/Rac1/Akt Pathway

Toll-like receptor 4 (TLR4) are important in inflammation and regulating vascular smooth muscle cells (VSMCs) proliferation, which are related to atherosclerosis and restenosis. We have investigated the mechanisms involved in Lipopolysaccharide (LPS)-induced proliferation of VSMCs. Stimulation of ra...

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Detalhes bibliográficos
Main Authors: Jiang, Dehua, Li, Dongye, Cao, Lijuan, Wang, Lele, Zhu, Shasha, Xu, Tongda, Wang, Cheng, Pan, Defeng
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3965409/
https://ncbi.nlm.nih.gov/pubmed/24667766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0092398
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