GABA and Glutamate Pathways Are Spatially and Developmentally Affected in the Brain of Mecp2-Deficient Mice

Proper brain functioning requires a fine-tuning between excitatory and inhibitory neurotransmission, a balance maintained through the regulation and release of glutamate and GABA. Rett syndrome (RTT) is a rare genetic disorder caused by mutations in the methyl-CpG binding protein 2 (MECP2) gene affe...

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Bibliographic Details
Main Authors: El-Khoury, Rita, Panayotis, Nicolas, Matagne, Valérie, Ghata, Adeline, Villard, Laurent, Roux, Jean-Christophe
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3965407/
https://ncbi.nlm.nih.gov/pubmed/24667344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0092169
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