Calcineurin/NFAT Signaling Represses Genes Vamp1 and Vamp2 via PMCA-Dependent Mechanism during Dopamine Secretion by Pheochromocytoma Cells

BACKGROUND: Plasma membrane Ca(2+)-ATPases (PMCA) extrude Ca(2+) ions out of the cell and contribute to generation of calcium oscillations. Calcium signaling is crucial for transcriptional regulation of dopamine secretion by neuroendocrine PC12 cells. Low resting [Ca(2+)](c) in PC12 cells is maintai...

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Detaylı Bibliyografya
Asıl Yazarlar: Kosiorek, Michalina, Zylinska, Ludmila, Zablocki, Krzysztof, Pikula, Slawomir
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2014
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3965406/
https://ncbi.nlm.nih.gov/pubmed/24667359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0092176
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