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Diverse Mechanisms of Wnt Activation and Effects of Pathway Inhibition on Proliferation of Human Gastric Carcinoma Cells

Human gastric carcinomas are among the most treatment refractory epithelial malignancies. Increased understanding of the underlying molecular aberrations in such tumors could provide insights leading to improved therapeutic approaches. In this study, we characterized diverse genetic aberrations lead...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Asciutti, Stefania, Akiri, Gal, Grumolato, Luca, Vijayakumar, Sapna, Aaronson, Stuart A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3965355/
https://ncbi.nlm.nih.gov/pubmed/21042278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2010.475
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