Diverse Mechanisms of Wnt Activation and Effects of Pathway Inhibition on Proliferation of Human Gastric Carcinoma Cells

Por Asciutti, Stefania, Akiri, Gal, Grumolato, Luca, Vijayakumar, Sapna, Aaronson, Stuart A.
Publicado em 2010

Analysis of Endogenous LRP6 Function Reveals a Novel Feedback Mechanism by Which Wnt Negatively Regulates Its Receptor

Por Khan, Zahid, Vijayakumar, Sapna, de la Torre, Teresa Villanueva, Rotolo, Sabrina, Bafico, Anna
Publicado em 2007

Canonical Wnts function as potent regulators of osteogenesis by human mesenchymal stem cells

Por Liu, Guizhong, Vijayakumar, Sapna, Grumolato, Luca, Arroyave, Randy, Qiao, HuiFang, Akiri, Gal, Aaronson, Stuart A.
Publicado em 2009

Wnt signaling is activated at high frequency and drives proliferation of multiple human sarcoma subtypes through a TCF/β-catenin target gene, CDC25A

Por Vijayakumar, Sapna, Liu, Guizhong, Rus, Ioana A., Yao, Shen, Chen, Yan, Akiri, Gal, Grumolato, Luca, Aaronson, Stuart A.
Publicado em 2011

Canonical and noncanonical Wnts use a common mechanism to activate completely unrelated coreceptors

Por Grumolato, Luca, Liu, Guizhong, Mong, Phyllus, Mudbhary, Raksha, Biswas, Romi, Arroyave, Randy, Vijayakumar, Sapna, Economides, Aris N., Aaronson, Stuart A.
Publicado em 2010

Extracellular LDLR repeats modulate Wnt signaling activity by promoting LRP6 receptor endocytosis mediated by the Itch E3 ubiquitin ligase

Por Vijayakumar, Sapna, Liu, Guizhong, Wen, Huei-Chi, Abu, Yaa, Chong, Robert, Nastri, Horacio, Bornstein, Gadi G., Pan, Zhen-Qiang, Aaronson, Stuart A.
Publicado no Genes Cancer (2017)