G-Quadruplex DNA as a Molecular Target for Induced Synthetic Lethality in Cancer Cells

[Image: see text] Synthetic lethality is a genetic concept in which cell death is induced by the combination of mutations in two sensitive genes, while mutation of either gene alone is not sufficient to affect cell survival. Synthetic lethality can also be achieved “chemically” by combination of dru...

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Detaylı Bibliyografya
Asıl Yazarlar: McLuckie, Keith I. E., Di Antonio, Marco, Zecchini, Heather, Xian, Jian, Caldas, Carlos, Krippendorff, Ben-Fillippo, Tannahill, David, Lowe, Christopher, Balasubramanian, Shankar
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Chemical Society 2013
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3964824/
https://ncbi.nlm.nih.gov/pubmed/23782415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja404868t
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