Transcriptome In Vivo Analysis (TIVA) of spatially defined single cells in intact live mouse and human brain tissue

Transcriptome profiling is an indispensable tool in advancing the understanding of single cell biology, but depends upon methods capable of isolating mRNA at the spatial resolution of a single cell. Current capture methods lack sufficient spatial resolution to isolate mRNA from individual in vivo re...

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Hlavní autoři: Lovatt, Ditte, Ruble, Brittani K., Lee, Jaehee, Dueck, Hannah, Kim, Tae Kyung, Fisher, Stephen, Francis, Chantal, Spaethling, Jennifer M., Wolf, John A., Grady, M. Sean, Ulyanova, Alexandra V., Yeldell, Sean B., Griepenburg, Julianne C., Buckley, Peter T., Kim, Junhyong, Sul, Jai-Yoon, Dmochowski, Ivan J., Eberwine, James
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3964595/
https://ncbi.nlm.nih.gov/pubmed/24412976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.2804
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