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Elevated Mouse Hepatic Betatrophin Expression Does Not Increase Human β-Cell Replication in the Transplant Setting

The recent discovery of betatrophin, a protein secreted by the liver and white adipose tissue in conditions of insulin resistance and shown to dramatically stimulate replication of mouse insulin-producing β-cells, has raised high hopes for the rapid development of a novel therapeutic approach for th...

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Detalhes bibliográficos
Main Authors: Jiao, Yang, Le Lay, John, Yu, Ming, Naji, Ali, Kaestner, Klaus H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3964501/
https://ncbi.nlm.nih.gov/pubmed/24353178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db13-1435
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