CypA, a Gene Downstream of HIF-1α, Promotes the Development of PDAC

Hypoxia-inducible factor-1α (HIF-1α) is a highly important transcription factor involved in cell metabolism. HIF-1α promotes glycolysis and inhibits of mitochondrial respiration in pancreatic ductal adenocarcinoma (PDAC). In response to tumor hypoxia, cyclophilin A (CypA) is over-expressed in variou...

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Autors principals: Zhang, Huan, Chen, Jing, Liu, Fenghua, Gao, Chuntao, Wang, Xiuchao, Zhao, Tiansuo, Liu, Jingcheng, Gao, Song, Zhao, Xiao, Ren, He, Hao, Jihui
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3963943/
https://ncbi.nlm.nih.gov/pubmed/24662981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0092824
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