Nucleolar Organization, Ribosomal DNA Array Stability, and Acrocentric Chromosome Integrity Are Linked to Telomere Function

The short arms of the ten acrocentric human chromosomes share several repetitive DNAs, including ribosomal RNA genes (rDNA). The rDNA arrays correspond to nucleolar organizing regions that coalesce each cell cycle to form the nucleolus. Telomere disruption by expressing a mutant version of telomere...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Stimpson, Kaitlin M., Sullivan, Lori L., Kuo, Molly E., Sullivan, Beth A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2014
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3963894/
https://ncbi.nlm.nih.gov/pubmed/24662969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0092432
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