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Nucleolar Organization, Ribosomal DNA Array Stability, and Acrocentric Chromosome Integrity Are Linked to Telomere Function

The short arms of the ten acrocentric human chromosomes share several repetitive DNAs, including ribosomal RNA genes (rDNA). The rDNA arrays correspond to nucleolar organizing regions that coalesce each cell cycle to form the nucleolus. Telomere disruption by expressing a mutant version of telomere...

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Bibliografiska uppgifter
Huvudupphovsmän: Stimpson, Kaitlin M., Sullivan, Lori L., Kuo, Molly E., Sullivan, Beth A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3963894/
https://ncbi.nlm.nih.gov/pubmed/24662969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0092432
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