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Comparison of Genome-Wide Association Methods in Analyses of Admixed Populations with Complex Familial Relationships
Population structure is known to cause false-positive detection in association studies. We compared the power, precision, and type-I error rates of various association models in analyses of a simulated dataset with structure at the population (admixture from two populations; P) and family (K) levels...
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Main Authors: | , , , |
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Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
Public Library of Science
2014
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3963841/ https://ncbi.nlm.nih.gov/pubmed/24662750 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0088926 |
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