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Weighting sequence variants based on their annotation increases the power of genome-wide association studies in dairy cattle
BACKGROUND: Genome-wide association studies (GWAS) are widely used to identify regions of the genome that harbor genetic determinants of quantitative traits. However, the multiple-testing burden from scanning tens of millions of whole-genome sequence variants reduces the power to identify associated...
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| Publicado no: | Genet Sel Evol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6511139/ https://ncbi.nlm.nih.gov/pubmed/31077144 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12711-019-0463-9 |
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