Phase II Clinical and Pharmacologic Study of Radiation Therapy and Carboxyamido-triazole (CAI) in Adults with Newly Diagnosed Glioblastoma Multiforme(1)

INTRODUCTION: Carboxyamido-triazole (CAI) is a synthetic inhibitor of non-voltage-gated calcium channels that reversibly inhibits angiogenesis, tumor cell proliferation, and metastatic potential. This study examined the efficacy, safety and pharmacokinetics of oral CAI in the treatment of patients w...

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Hauptverfasser: Mikkelsen, Tom, Lush, Richard, Grossman, Stuart A., Carson, Kathryn A., Fisher, Joy D., Alavi, Jane B., Rosenfeld, Steve
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2006
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3963813/
https://ncbi.nlm.nih.gov/pubmed/17080256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10637-006-9023-6
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