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c-Src Kinase Inhibition Reduces Arrhythmia Inducibility and Connexin43 Dysregulation after Myocardial Infarction

OBJECTIVES: The aim of this study was to evaluate the role of c-Src inhibition on connexin43 (Cx43) regulation in a mouse model of myocardial infarction (MI). BACKGROUND: MI is associated with decreased expression of Cx43, the principal gap junction protein responsible for propagating current in ven...

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Bibliografiske detaljer
Main Authors: Rutledge, Cody A., Ng, Fu Siong, Sulkin, Matthew S., Greener, Ian D., Sergeyenko, Artem M., Liu, Hong, Gemel, Joanna, Beyer, Eric C., Sovari, Ali A., Efimov, Igor R., Dudley, Samuel C.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3963804/
https://ncbi.nlm.nih.gov/pubmed/24361364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2013.10.081
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