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c-Src Kinase Inhibition Reduces Arrhythmia Inducibility and Connexin43 Dysregulation after Myocardial Infarction

OBJECTIVES: The aim of this study was to evaluate the role of c-Src inhibition on connexin43 (Cx43) regulation in a mouse model of myocardial infarction (MI). BACKGROUND: MI is associated with decreased expression of Cx43, the principal gap junction protein responsible for propagating current in ven...

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Detalhes bibliográficos
Main Authors: Rutledge, Cody A., Ng, Fu Siong, Sulkin, Matthew S., Greener, Ian D., Sergeyenko, Artem M., Liu, Hong, Gemel, Joanna, Beyer, Eric C., Sovari, Ali A., Efimov, Igor R., Dudley, Samuel C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3963804/
https://ncbi.nlm.nih.gov/pubmed/24361364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2013.10.081
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