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Modulation of an ectodomain motif in the influenza A virus neuraminidase alters tetherin sensitivity and results in virus attenuation in vivo
We previously demonstrated that ectodomain residue Asp(286) in N2 neuraminidase (NA; Asp(268) in N1 NA) present in budding-capable NA proteins contributes to productive NA plasma membrane transport partly by mediating escape from tetherin restriction(1). Budding-incapable NA proteins contain a G at...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3963499/ https://ncbi.nlm.nih.gov/pubmed/24380762 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2013.12.023 |
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