Molecular and Population Analysis of Natural Selection on the Human Haptoglobin Duplication

Haptoglobin binds free haemoglobin that prevents oxidative damage produced by haemolysis. There is a copy number variant (CNV) in the haptoglobin gene (HP) consisting of two alleles, Hp1 (no duplication), and Hp2 (1.7kb duplication involving two exons). The spread of the Hp2 allele is believed to ha...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Rodriguez, Santiago, Williams, Dylan M, Guthrie, Philip AI, McArdle, Wendy L, Smith, George Davey, Evans, David M, Gaunt, Tom R, Day, Ian NM
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2012
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3963445/
https://ncbi.nlm.nih.gov/pubmed/22607059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-1809.2012.00716.x
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados