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Complexity of a complex trait locus: HP, HPR, haemoglobin and cholesterol
HP and HPR are related and contiguous genes in strong linkage disequilibrium (LD), encoding haptoglobin and haptoglobin-related protein. These bind and chaperone free Hb for recycling, protecting against oxidation. A copy number variation (CNV) within HP (Hp1/Hp2) results in different possible hapto...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier/North-Holland
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3405512/ https://ncbi.nlm.nih.gov/pubmed/22433445 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gene.2012.03.034 |
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