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Bcl-2 level as a biomarker for 13q14 deletion in CLL
BACKGROUND: Deletion 13q14.3 is the most common cytogenetic abnormality in chronic lymphocytic leukemia (CLL). Previously it was reported that miR-15/16 is the target of 13q14 deletions and plays a tumor suppressor role by suppressing Bcl-2. Therefore, Bcl-2 expression was examined more closely to d...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3963274/ https://ncbi.nlm.nih.gov/pubmed/23674504 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cyto.b.21090 |
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