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Synthesis of 4-aryl-6-indolylpyridine-3-carbonitriles and evaluation of their antiproliferative activity

A novel class of 6-indolypyridine-3-carbonitrilile derivatives were synthesized and evaluated for antiproliferative activities to establish structure-activity relationship. The synthesis was carried out through one-pot multicomponent reaction of 3-acetylindole, aromatic aldehydes, ethyl cyanoacetate...

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Bibliographische Detailangaben
Hauptverfasser: El-Sayed, Naglaa Salem, Shirazi, Amir Nasrolahi, El-Meligy, Magda Goda, El-Ziaty, Ahmed Kamel, Nagib, Zenat Adeeb, Parang, Keykavous
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3963174/
https://ncbi.nlm.nih.gov/pubmed/24678129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2013.12.081
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