Synthesis and Structure–Activity Relationships of N-Benzyl Phenethylamines as 5-HT(2A/2C) Agonists

[Image: see text] N-Benzyl substitution of 5-HT(2A) receptor agonists of the phenethylamine structural class of psychedelics (such as 4-bromo-2,5-dimethoxyphenethylamine, often referred to as 2C-B) confer a significant increase in binding affinity as well as functional activity of the receptor. We h...

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Autors principals: Hansen, Martin, Phonekeo, Karina, Paine, James S., Leth-Petersen, Sebastian, Begtrup, Mikael, Bräuner-Osborne, Hans, Kristensen, Jesper L.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2014
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3963123/
https://ncbi.nlm.nih.gov/pubmed/24397362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn400216u
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